|
|
S-adenosyl-L-methionine + uroporphyrinogen_III <=> H+ + S-adenosyl-L-homocysteine + precorrin-1
|
2.1.1.107
uroporphyrinogen-III C-methyltransferase
|
–
|
| |
BRENDA:
BR43866
KEGG:
R07237
MetaCyc:
UROPORIIIMETHYLTRANSA-RXN
|
|
|
|
S-adenosyl-L-methionine + precorrin-2 <=> H+ + S-adenosyl-L-homocysteine + precorrin-3A
|
2.1.1.130
precorrin-2 C20-methyltransferase
|
–
|
| |
BRENDA:
BR1453
KEGG:
R03948
MetaCyc:
2.1.1.130-RXN
|
|
|
|
S-adenosyl-L-methionine + precorrin-5 + H2O <=> H+ + precorrin-6A + S-adenosyl-L-homocysteine + acetate
|
2.1.1.152
precorrin-6A synthase (deacetylating)
|
–
|
| |
BRENDA:
BR47993
KEGG:
R05219
MetaCyc:
R322-RXN
|
|
|
|
S-adenosyl-L-methionine + precorrin-4 <=> precorrin-5 + S-adenosyl-L-homocysteine + H+
|
2.1.1.133
precorrin-4 C11-methyltransferase
2.1.1.271
cobalt-precorrin-4 methyltransferase
|
–
–
|
| |
BRENDA:
BR6348
KEGG:
R05181
MetaCyc:
2.1.1.133-RXN
|
|
|
|
S-adenosyl-L-methionine + precorrin-3B <=> H+ + precorrin-4 + S-adenosyl-L-homocysteine
|
2.1.1.131
precorrin-3B C17-methyltransferase
|
–
|
| |
BRENDA:
BR1454
KEGG:
R05180
MetaCyc:
2.1.1.131-RXN
|
|
|
|
S-adenosyl-L-methionine + precorrin-1 <=> S-adenosyl-L-homocysteine + precorrin-2
|
2.1.1.107
uroporphyrinogen-III C-methyltransferase
|
–
|
| |
BRENDA:
BR49530
KEGG:
R07238
MetaCyc:
RXN-8675
|
|
|
|
H+ + precorrin-8X <=> Hydrogenobyrinate
|
5.4.99.61
precorrin-8X methylmutase
|
–
|
| |
BRENDA:
BR16
KEGG:
R05177
MetaCyc:
5.4.1.2-RXN
SABIO-RK:
4794
|
|
|
|
S-adenosyl-L-methionine + Precorrin-6Y + H+ <=> precorrin-7 + S-adenosyl-L-homocysteine + CO2
|
2.1.1.132
precorrin-6B C5,15-methyltransferase (decarboxylating)
|
–
|
| |
BRENDA:
BR50363
MetaCyc:
RXN-13824
|
|
|
|
precorrin-3A + O2 + NADH + H+ <=> precorrin-3B + H2O + NAD+
|
1.14.13.83
precorrin-3B synthase
|
–
|
| |
BRENDA:
BR47982
KEGG:
R05217
MetaCyc:
R321-RXN
|
|
|
|
S-adenosyl-L-methionine + precorrin-7 <=> precorrin-8X + S-adenosyl-L-homocysteine + H+
|
2.1.1.132
precorrin-6B C5,15-methyltransferase (decarboxylating)
|
–
|
| |
BRENDA:
BR50364
MetaCyc:
RXN-13826
|
|
|
|
Hydrogenobyrinate + L-glutamine + ATP + H2O <=> H+ + L-glutamate + hydrogenobyrinic_acid_a,c-diamide + ADP + phosphate
|
6.3.5.11
cobyrinate a,c-diamide synthase
6.3.5.9
hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)
|
–
–
|
| |
BRENDA:
BR48014
KEGG:
R05224
MetaCyc:
R341-RXN
SABIO-RK:
4835
|
|
|
|
hydrogenobyrinic_acid_a,c-diamide + Co2+ + ATP + H2O <=> H+ + cob(II)yrinic_acid_a,c-diamide + ADP + phosphate
|
6.6.1.2
cobaltochelatase
|
–
|
| |
BRENDA:
BR48015
KEGG:
R05227
MetaCyc:
R342-RXN
|
|
|
|
Precorrin-6Y + NADP+ <=> precorrin-6A + NADPH + H+
|
1.3.1.54
precorrin-6A reductase
|
–
|
| |
BRENDA:
BR1202
KEGG:
R05150
MetaCyc:
1.3.1.54-RXN
|
|
